Yohei Kirino Selected Research

5-taurinomethyluridine

7/2008	Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding.
5/2005	Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease.

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Yohei Kirino Research Topics

Disease

8	Inflammation (Inflammations) 01/2022 - 04/2006
7	Neoplasms (Cancer) 07/2021 - 01/2012
7	Rheumatoid Arthritis 11/2019 - 04/2006
6	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2021 - 08/2017
6	MELAS Syndrome (Syndrome, MELAS) 07/2008 - 10/2004
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 10/2004
4	Ulcer 10/2022 - 06/2010
4	Adult-Onset Still's Disease 08/2022 - 01/2005
3	Arthritis (Polyarthritis) 10/2022 - 01/2022
3	Infections 08/2022 - 09/2020
3	Relapsing Polychondritis 01/2022 - 01/2021
3	VEXAS syndrome 01/2022 - 11/2021
3	Breast Neoplasms (Breast Cancer) 12/2019 - 07/2015
2	Oral Ulcer (Mouth Ulcer) 10/2022 - 07/2021
2	Systemic Scleroderma (Systemic Sclerosis) 03/2022 - 06/2010
2	Psychotic Disorders (Schizoaffective Disorder) 01/2022 - 01/2021
2	Disease Progression 01/2022 - 02/2003
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022 - 01/2022
2	Familial Mediterranean Fever (Periodic Disease) 12/2021 - 05/2013
2	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2021 - 09/2020
2	Dermatomyositis (Dermatopolymyositis) 01/2021 - 09/2020
2	Rheumatic Diseases (Rheumatism) 01/2021 - 01/2005
2	Ankylosing Spondylitis 05/2019 - 02/2013
2	Psoriasis (Pustulosis Palmaris et Plantaris) 05/2019 - 02/2013
2	Lung Neoplasms (Lung Cancer) 01/2019 - 02/2003
2	Carcinogenesis 03/2016 - 07/2015
2	Prostatic Neoplasms (Prostate Cancer) 03/2016 - 07/2015
2	Behcet Syndrome (Behcet's Syndrome) 06/2014 - 05/2013
2	MERRF Syndrome (Myoclonic Epilepsy and Ragged Red Fibers) 05/2005 - 04/2005
1	Oral Manifestations 10/2022
1	Erythema Nodosum 10/2022
1	Skin Ulcer 10/2022
1	Edema (Dropsy) 08/2022
1	POEMS Syndrome (Syndrome, POEMS) 08/2022
1	Fibrosis (Cirrhosis) 08/2022
1	Polyneuropathies (Polyneuropathy) 08/2022
1	Thrombocytopenia (Thrombopenia) 08/2022
1	Neurologic Manifestations (Neurological Manifestations) 01/2022
1	Paralysis (Palsy) 01/2022
1	Nausea 07/2021
1	Disseminated Intravascular Coagulation 07/2021
1	Pleurisy (Pleuritis) 07/2021
1	Necrosis 07/2021
1	Myasthenia Gravis 01/2021
1	Exanthema (Rash) 01/2021
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Myocarditis (Carditis) 01/2021
1	Myositis (Idiopathic Inflammatory Myopathies) 01/2021
1	Cognitive Dysfunction 01/2021
1	Iridocyclitis 01/2021
1	Arthralgia (Joint Pain) 01/2021

Drug/Important Bio-Agent (IBA)

10	Transfer RNA (tRNA)IBA 01/2020 - 10/2004
7	Proteins (Proteins, Gene)FDA Link 08/2022 - 03/2009
6	EnzymesIBA 01/2022 - 04/2006
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 07/2015
5	Leu Transfer RNAIBA 03/2006 - 10/2004
5	Taurine FDA Link 05/2005 - 01/2003
4	Prednisolone (Predate)FDA LinkGeneric 10/2022 - 03/2009
4	Heme (Haem)IBA 10/2018 - 01/2005
4	Heme Oxygenase-1IBA 09/2018 - 04/2006
4	AnticodonIBA 05/2005 - 10/2004
3	Ferritins (Ferritin)IBA 07/2021 - 01/2005
3	Interleukin-10 (Interleukin 10)IBA 12/2018 - 02/2013
3	Codon (Codons)IBA 03/2006 - 10/2004
3	UridineIBA 05/2005 - 01/2003
2	apremilastIBA 10/2022 - 07/2021
2	Pharmaceutical PreparationsIBA 08/2022 - 07/2021
2	InterferonsIBA 08/2022 - 11/2018
2	tocilizumab (atlizumab)FDA Link 01/2022 - 11/2021
2	GlucocorticoidsIBA 01/2022 - 01/2021
2	Interferon Type IIBA 11/2021 - 10/2018
2	AutoantigensIBA 11/2021 - 01/2020
2	Immunosuppressive Agents (Immunosuppressants)IBA 07/2021 - 01/2021
2	HLA-B Antigens (HLA-B)IBA 12/2018 - 06/2014
2	Glucose (Dextrose)FDA LinkGeneric 08/2017 - 01/2009
2	Hormones (Hormone)IBA 03/2016 - 07/2015
2	Gonadal Steroid Hormones (Sex Hormones)IBA 03/2016 - 07/2015
2	AntigensIBA 06/2014 - 03/2009
2	5-taurinomethyluridineIBA 07/2008 - 05/2005
2	Lys Transfer RNAIBA 05/2005 - 04/2005
1	SteroidsIBA 10/2022
1	C-Reactive ProteinIBA 08/2022
1	Reticulin (Reticular Fiber)IBA 08/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	PyrinIBA 12/2021
1	Colchicine FDA LinkGeneric 07/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021
1	LigandsIBA 01/2021
1	AutoantibodiesIBA 01/2021
1	AntibodiesIBA 01/2021
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2021
1	anti-dsDNA autoantibodyIBA 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	HLA-A*26 antigenIBA 01/2021
1	Interleukin-18 (Interleukin 18)IBA 01/2021
1	UbiquitinIBA 01/2021

Therapy/Procedure

2	Therapeutics 03/2009 - 02/2003
1	Hematopoietic Stem Cell Transplantation 03/2022
1	Activities of Daily Living (ADL) 01/2022